Topical beta-adrenergic receptor antagonists decrease aqueous humor production by the ciliary body. Adverse effects are due to systemic absorption of the drug, decreased cardiac output, and bronchoconstriction. In susceptible patients, this may cause bronchospasm, bradycardia, heart block, or hypotension. Monitor the patient's pulse rate and blood pressure; patients may be instructed to perform punctal occlusion after administering the drops. Depression or anxiety may be experienced in some patients, and sexual dysfunction may be initiated or exacerbated.
Douglas J Rhee, MD Chair and Professor, Department of Ophthalmology and Visual Science, University Hospitals Eye Institute, Case Western Reserve University School of Medicine
Douglas J Rhee, MD is a member of the following medical societies: Alpha Omega Alpha , Association for Research in Vision and Ophthalmology , American Glaucoma Society , American Academy of Ophthalmology , American Medical Association , Phi Beta Kappa
Disclosure: Received grant/research funds from Alcon for independent contractor; Received grant/research funds from Allergan for independent contractor; Received consulting fee from Alcon for consulting; Received consulting fee from Allergan for consulting; Received grant/research funds from Merck for independent contractor; Received grant/research funds from Ivantis for independent contractor; Received consulting fee from Glaukos for consulting; Received consulting fee from Ivantis for consulting; Received.