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The 1970s brought about many developments in hardware and instrumentation. Researchers began using pumps and injectors to make a rudimentary design of an HPLC system.  Gas amplifier pumps were ideal because they operated at constant pressure and did not require leak free seals or check valves for steady flow and good quantitation.  Hardware milestones were made at Dupont IPD (Industrial Polymers Division) such as a low-dwell-volume gradient device being utilized as well as replacing the septum injector with a loop injection valve.