IgA Nephropathy (IgAN) has varied clinical presentations from asymptomatic microscopic hematuria to rapidly progressive crescentic glomerulonephritis. Almost 30% of patients ultimately progress to ESKD within 20 years. Geographical variability in long-term outcome of IgAN is partly explained by lead-time bias and inclusion of milder cases in centers with good outcomes. Conservative treatment has proven to be very effective in IgAN, as shown in STOP-IgAN trial , where almost one third of patients who completed intensive optimization of conservative therapy over 6 months period, no longer qualified for randomization to the immunosuppressive therapy arm of the trial.
Despite all positive effects of doping on the body they could be dangerous. Possible side effects of anabolic steroids can be avoided by choosing the right form (oral or injectable) and combination as well as by taking reasonable androgenic dosages. It has to be mentioned, that the most side effects of drugs disappear after the cycle is completed. Moreover, many of them can be blocked during the cycle by using respective supplements. Therefore, in order to avoid possible negative consequences one shall pay attention to studying information about the drugs prior to use them.
Amen John Harrington and Andrew. There are much more important things for our Congress to be working on than baseball. We are just wasting our tax dollars here. Why won’t they tackle a much more important issue. For example: healthcare, gas prices, subprime scandal, recession, Iraq and Afganistan Wars, loss of manufacturing jobs, etc… I don’t think steroids in baseball ranks above any that I have mentioned. What is the ROI on this investigation? I would rather know that my kid will have a country to inherit, that still speaks English and not Chinese or Arabic in 15 years.