The program has various advantages over other diets, which make it much easier and realistic to follow. Our program offers variation, thus, it won't be boring to follow; it doesn't promote a lifestyle that prevents you from functioning in a social context; it's based on legitimate scientific finding; it's been tested on over 100 Test Subjects; bodybuilders have been exploiting The Anabolic Amplifier Effect for 50 to 60 years now; the "perfect" macronutrient ratios are not as important as the total goal calories in each phase (far easier to tackle); and the program allows you to make changes within the 21-day framework of the diet and training in terms of your individual ambitions and goals.
This initial case report of severe hepatitis attributed to chaparral use was published 7 years after its occurrence in 1983. A young woman developed a severe viral hepatitis-like syndrome 3 months after starting chaparral and had a temporary improvement on lowering the dose, and subsequent worsening with increasing it. Serum liver tests were not available from these periods of dose adjustment, but the clinical history suggested an association of disease severity with dosage and a positive rechallenge. When she presented to medical evaluation, she had evidence of severe hepatitis with jaundice and marked serum aminotransferase elevations along with ascites and prolongation of the prothrombin time. She began to improve between 1 and 2 weeks after stopping chaparral. A liver biopsy documented the severity of the liver injury (submassive necrosis with an estimated 60% loss of parenchyma). Symptoms and minor serum enzyme elevations persisted for at least 4 months after stopping, with full documentation of resolution when she was seen a year after stopping chaparral. The component of chaparral leaf extracts that is responsible for hepatotoxicity is not known; features of the disease suggest that the liver injury is idiosyncratic rather than a direct toxic effect.