3ketosteroid receptors

Fellow, Society for Risk Analysis

Outstanding Service Award, Society for Risk Analysis, 2012

Senior Fellow, Department of Epidemiology, University of Washington, 1976–1977

Postdoctoral Fellow, Departments of Pharmacology and Biophysics, Johns Hopkins Medical School, Baltimore, Maryland, 1966-1968

Elected Member, American Epidemiological Society

Distinguished Achievement Award, Society for Risk Analysis, 2001

Founders’ Award, Chemical Industry Institute of Toxicology, 1990

Lester R. Ford Award of Mathematical Association of America, 1977

Faculty Research Fellowship of Indiana University, 1974–1976

Sex hormone-binding globulin (SHBG) is thought to mainly function as a transporter and reservoir for the estradiol and testosterone sex hormones. However it has also been demonstrated that SHBG can bind to a cell surface receptor (SHBG-R). The SHBG-R has not been completely characterized. A subset of steroids are able to bind to the SHBG/SHBG-R complex resulting in an activation of adenylyl cyclase and synthesis of the cAMP second messenger. [19] Hence the SHBG/SHBG-R complex appears to act as a transmembrane steroid receptor that is capable of transmitting signals to the interior of cells.

3ketosteroid receptors

3 ketosteroid receptors


3 ketosteroid receptors3 ketosteroid receptors3 ketosteroid receptors3 ketosteroid receptors3 ketosteroid receptors